Efficacy and safety of acupuncture combined with Chinese herbal medicine in the treatment of angina in coronary heart disease (CHD): a protocol for a systematic review and meta-analysis

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Medicine (Baltimore). December 30, 2021; 100 (52): e28450. doi: 10.1097 / MD.00000000000028450.

ABSTRACT

Background: Angina from coronary heart disease (CHD) is a clinical syndrome in which episodic chest pain or chest discomfort is the primary manifestation of temporary ischemia and myocardial hypoxia due to coronary atherosclerosis and functional changes in the coronary artery (spasm). Extensive clinical evidence confirms that acupuncture combined with Chinese herbal medicine in the treatment of coronary heart disease and angina pectoris can relieve symptoms of angina pectoris and improve performance of EKG ischemia; It still has evident therapeutic effects in the regulation of the levels of cardiovascular regulatory peptides ET and cGRP. In order to better assess the efficacy and safety of acupuncture combined with Chinese herbal medicine in the treatment of coronary heart disease and angina pectoris, we have designed a systematic evaluation program to provide a reliable scientific basis for future use of this method.

METHODS: Pubmed Research Database, Embase, Cochrane Library, Chinese Biomedical Literature CD-ROM Database (CBMdisk), China Journal Network (CNKI) Full Text Database, Wanfang Database, Web of Science (SCI-E), recovery time is established in each database Until October 2021, search for relevant eligible randomized controlled trials with keywords or subject terms “acupuncture”, “Chinese medicine based of plants ”and“ CHD angina ”. Outcome indicators were clinical symptoms of coronary artery disease and angina pectoris, changes in the EKG, changes in blood lipids, and significant improvement in traditional Chinese medicine syndromes before and after treatment. Two researchers independently performed data extraction and quality assessment, and use RevMan5.3 software to perform final data analysis and assessment.

RESULTS: This study provides a reliable clinical scientific basis for acupuncture combined with Chinese herbal medicine for the treatment of coronary heart disease and angina pectoris.

Conclusion: Acupuncture combined with Chinese herbal medicine can effectively relieve clinical symptoms of coronary heart disease and angina pectoris and improve the performance of the EKG machine. At the same time, it can reduce the cardiovascular regulatory peptide ET and increase the level of cGRP in the patient’s plasma, thus confirming its efficacy and safety.

PMID: 34967384 | DOI: 10.1097 / MD.00000000000028450


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